Useful Links & Tools
- MSDS
- Certificate of Analysis
- Certificate of Origin
- DNA and RNA Guide (519 KB )
- FT-IR Raman
- FT-NMR
- Bulk Quote
B9673
Sigma
1-Bromo-3-chloropropane
| Synonym: | I-BCP, Trimethylene bromochloride, Trimethylene chlorobromide |
| CAS Number: | 109-70-6 |
| Linear Formula: | Cl(CH2)3Br |
| Molecular Weight: | 157.44 |
| Beilstein Registry Number: | 605278 |
| EC Number: | 203-697-1 |
| MDL number: | MFCD00000998 |
| PubChem Substance ID: | 24892149 |
Description
| Application | BCP can be used in place of chloroform, and is less toxic. The use of BCP in the single-step TRI® Reagent method decreases the possibility of contaminating RNA with DNA. It does not adversely affect quality or quantity of the isolated RNA. |
Properties
| refractive index | n |
| bp | 144-145 °C(lit.) |
| density | 1.592 g/mL at 25 °C(lit.) |
Safety
References
| reference | Chomczynski, P. and Mackey, K, Substitution of chloroform by bromo-chloropropane in the single-step method of RNA isolation. Anal. Biochem. 225, 163-164, (1995) Abstract |
| Beilstein | Beil. 1,IV,212 |
| Aldrich MSDS 1, 242:C / Corp MSDS 1 (1), 516:D / FT-IR 2 (1), 104:D / FT-IR 1 (1), 73:C / FT-NMR 1 (1), 108:C / IR-Spectra (2), 46:E / IR-Spectra (3), 48:F / NMR-Reference 2 (1), 74:D / RegBook 1 (1), 71:L / Structure Index 1, 8:A:10 / Vapor Phase 3, 104:D |






