B9673

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B9673

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1-Bromo-3-chloropropane

Synonym:I-BCP, Trimethylene bromochloride, Trimethylene chlorobromide
CAS Number:109-70-6
Linear Formula:Cl(CH2)3Br
Molecular Weight:157.44
Beilstein Registry Number:605278
EC Number:203-697-1
MDL number:MFCD00000998
PubChem Substance ID:24892149

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Description

ApplicationBCP can be used in place of chloroform, and is less toxic. The use of BCP in the single-step TRI® Reagent method decreases the possibility of contaminating RNA with DNA. It does not adversely affect quality or quantity of the isolated RNA.

Properties

refractive indexn20/D 1.486(lit.)
bp144-145 °C(lit.)
density1.592 g/mL at 25 °C(lit.)

Safety

Hazard CodesXn
Risk Statements10-22
Safety Statements16
RIDADRUN 2688 6.1/PG 3
WGK Germany3
RTECSTX4113000
Flash Point(F)113 °F
Flash Point(C)45 °C

References

referenceChomczynski, P. and Mackey, K, Substitution of chloroform by bromo-chloropropane in the single-step method of RNA isolation. Anal. Biochem. 225, 163-164, (1995) Abstract
BeilsteinBeil. 1,IV,212
 Aldrich MSDS 1, 242:C / Corp MSDS 1 (1), 516:D / FT-IR 2 (1), 104:D / FT-IR 1 (1), 73:C / FT-NMR 1 (1), 108:C / IR-Spectra (2), 46:E / IR-Spectra (3), 48:F / NMR-Reference 2 (1), 74:D / RegBook 1 (1), 71:L / Structure Index 1, 8:A:10 / Vapor Phase 3, 104:D